Creating A Better Alternative to Dialysis

Our mission is to restore freedom, function, and independence in individuals with end stage kidney disease.

Holly™ is DESIGNED TO WORK Like a kidney

“An implantable continuous dialysis hemofiltration device blending hemodialysis and peritoneal dialysis in one device.”

The goal of our technology is to serve as a more effective renal replacement therapeutic as it minimizes the burden of treatment, facilitates mobility, and reduces potential infection complications.

Improving Quality of Care

The Holly™ is not yet commercially available. Once available, eligibility to receive our device, Holly™ will be determined by an individual’s healthcare team including Nephrodite’s team of highly qualified health care provider experts. Once selected, a thorough discussion including device training and how to use it will be conducted with each patient and her/his family members.

The implantable portion of Holly™ is designed to be placed by a team of Surgeons, typically a Vascular Access Surgeon. The hemofilter of Holly™ needs to be surgically connected to an artery in the pelvic area near the lower abdomen, typically on the right side.

The device will continuously filter blood.

In addition, catheter tubing from the implanted device will be brought out through the skin and will be connected to a bag of dialysate fluid on a wearable and detachable vest. Patients will be taught to exchange the dialysate bag from their externalized catheter, ideally, every 4-6 hours during the day. The device is also designed to be compatible with larger dialysate bags can be used while at home or at nighttime. This can reduce the number of exchanges that a patient needs to perform.

The dialysate bag will be held on a wearable, detachable vest or a backpack depending on patient preference. In addition, a power pack and a small pump will be located on the vest or backpack. A home-based mechanical unit will also be available that replaces the vest or backpack, if that is preferred.

Key Attributes

01

Continuous hemofiltration as opposed to intermittent dialysis

02

Maintenance and improvement of health outcomes avoiding the peaks and troughs related to the issues of urea levels and clearance in intermittent HD

03

Improved QOL with patients able to be mobile and free from in-center HD or abdominal infusions with PD

04

Avoidance of graft or fistula access and subsequent complications

05

Avoidance of PD catheter-related issues

Get to Know Holly™

Holly Device

Get In Touch

For general or research related questions, please contact Nephrodite via our contact form.

Nephrodite, Inc.
Centergy One Building
75 Fifth St., 2nd Floor, Suite 2408
Atlanta, GA 30308